Functional subsets of mesenchymal cell types in the tumor microenvironment

Functional subsets of mesenchymal cell types in the tumor microenvironment.

In the field of tumor biology, increasing attention is now focused on the complex interactions between various constituent cell types within the tumor microenvironment as being functionally important for the etiology of the disease. The detailed description of tumor-promoting properties of cancer-associated fibroblasts, endothelial cells, pericytes, and immune cells, introduces novel potential ...

T Cell and Antigen-Presenting Cell Subsets in the Tumor Microenvironment

The development of successful antitumor immunity depends upon cross talk and collaboration between multiple T cell and antigen-presenting cell subsets. In this chapter, we review and summarize current knowledge regarding the function, interactions, and prognostic significance of each of these populations, as well as their dependence upon one another within the tumor microenvironment. 2.1 Cytoto...

The Role of Mesenchymal Stem Cells in the Tumor Microenvironment

The roles of mesenchymal stem cells in tumor inflammatory microenvironment

Tumor behavior is not entirely determined by tumor cells. Studies have demonstrated that a variety of non-tumor cells in the tumor microenvironment affect tumor behavior; thus, a new focus of cancer research has been the development of novel cancer treatment ideas and therapeutic targets based on the effects of these cells. Mesenchymal stem cells (MSCs) are an important component of the tumor m...

the effect of functional/notional approach on the proficiency level of efl learners and its evaluation through functional test

in fact, this study focused on the following questions: 1. is there any difference between the effect of functional/notional approach and the structural approaches to language teaching on the proficiency test of efl learners? 2. can a rather innovative language test referred to as "functional test" ge devised so so to measure the proficiency test of efl learners, and thus be as much reliable an...